Integrated Project IV

Sustainable Development Goals (SDG)

• 3. Good health and well-being
• 5. Gender equality

Objectives

This subject belongs to a series of subjects, Integrated Projects I-VI, of the undergraduate program in Biomedicine which culminate each semester from the first to third year. The common objective of this set of subjects is to work at a practical level on the knowledge that students have acquired in other subjects during the semester, while facilitating the acquisition of skills related to biomedical research. The teaching methodology is problem- or project-based learning.

Specifically, Integrated Project IV is a research workshop related to the subjects of Omics Data and Bioinformatics I and Cell Signalling and Gene Regulation. For this reason, we strongly recommend that students enrolling in this subject have taken Omics Data and Bioinformatics I, and Cell Signalling and Gene Regulation.

Learning outcomes

• RA1. Use specialised information sources in science and technology in English.
• RA2. Manages databases and applies advanced statistical methods to analyse these data.
• RA3. Demonstrate comprehension of spoken and written scientific English.
• RA4. Recognise and apply the main guidelines for structuring presentations, projects and publications in scientific communication.
• RA5. Resolve problems and situations relevant to professional practice in an innovative and entrepreneurial manner.
• RA6. Design interventions to meet the needs of the area in a multidisciplinary way.
• RA7. Critically reflect on processes related to professional practice.
• RA8. Use appropriate spoken language (verbal and non-verbal) to communicate in personal and professional situations in Catalan, Spanish and English.
• RA9. Apply strategies to promote gender equality and justice in the workplace.
• RA10. Prepare reports and written documents (mainly of a technical nature) with correct spelling and grammar in Catalan, Spanish and English.

Competencies

General skills

• Show a positive attitude to innovating, creating value and integrating scientific knowledge and improving one's own training.

Specific skills

• Analyse biomedical data and biological sequences through the use of statistics and computation.
• Be able to critically interpret the results and conclusions of scientific studies.
• Formulate hypotheses and design experiments in the field of biomedical research.
• Have technical skill in a research laboratory for working on cell and tissue samples, and with experimental animals.
• Recognise the applicability of genetic engineering methods and omics technology in preclinical and clinical research.

Basic skills

• Students can apply their knowledge to their work or vocation in a professional manner and have competencies typically demonstrated through drafting and defending arguments and solving problems in their field of study.
• Students can communicate information, ideas, problems and solutions to both specialists and non-specialists.
• Students have developed the learning skills necessary to undertake further studies with a high degree of independent learning.

Core skills

• Develop strategies for promoting gender equality and equity for all.
• Exercise active citizenship and individual responsibility with a commitment to democratic values and sustainable development.
• Interact in international contexts to transfer knowledge to current and emerging fields of professional development and research.
• Reflect critically on knowledge of all kinds, with a commitment to professional rigour and quality.

Content

• Compare and analyze a DNA sequence
• Identification and characterization of a gene within the DNA sequence and its main important parts
• Identification and function of the encoded protein
• Metabolic routes or cell signaling pathways in which this protein participates
• Relationship with disease
  • Gene expression
  • Protein expression
  • Epidemiological analysis
  • Therapeutic implications

Evaluation

You will be assessed in the following way:

• Online tests: 30%
• Complementary activities: 10%
• Scientific presentation: 25%
• Scientific article: 25%
• Active participation: 10% (participation, attitude, attendance)

Attendance is compulsory. Absences are not allowed, but it is possible to miss 1 or 2 sessions for justified reasons. More than 2 unexcused absences mean failing the whole course.

Excused absences do not exclude students from doing the work derived from the session they did not attend.

Excused absences allowed are:

• Hospital admission
• Court summons
• Death of a family member of 1st or 2nd degree of consanguinity or affinity
• Medically diagnosed illness that makes it impossible to attend the session
• Attendance at a scheduled visit to the hospital, which cannot be postponed and which involves diagnosis, follow-up and/or medical treatment

In case of a justified absence

• If it is not possible to make up the class, the student must do a work (proposed by the teacher) that allows him/her to recover, totally or partially, the content of the session he/she has missed. The elaboration of this work is compulsory and the non-presentation of the work implies a penalty equivalent to the reduction of 5% of the final grade of the course.

In the case of unexcused absence

• It is not possible to recover the class and a penalty equivalent to the reduction of 10% of the final grade of the course for each session to which it is missed (therefore, one absence supposes a reduction of 10% of the final grade and two, one of 20%).
• Absence from 3 or more sessions means failing the course.
• The student can do a recommended work to recover, totally or partially, the content of the session to which he/she has missed, but it is not obligatory. If the student makes up the work satisfactorily, he/she can recover 5% of the penalty imposed for the absence.

Methodology

The course is based on problem-based learning (PBL) methodology, which involves both individual and group work in response to a challenge, analysing the data related to it and being able to propose a feasible solution.

Bibliography

Further reading

Teachers will provide complementary bibliography and compulsory reading throughout the course via the Virtual Campus.